Being a major gateway into the largest city of New Hampshire, the Manchester–Boston Regional Airport receives service from some of the largest airline companies in the United States. All of the airline ticketing counters are located on the First Floor of the main lobby that's located to the right of the entrance in the main terminal building. All airlines use the gates on the Second Level of the terminal building.
Delta Air Lines links Manchester–Boston Regional Airport with two major destinations on the East Coast. The company offers direct trips to the LaGuardia Airport, which is one of the three major airports serving the New York City Metropolitan Area. Delta also connects the largest airport in New Hampshire with Hartsfield-Jackson International Airport in Atlanta, Georgia. With direct trips to Detroit Wayne County Metropolitan Airport, Delta Air Lines invites Manchester's passengers to one of the largest cities in the Midwest region.
Southwest Airlines is proud to call itself the busiest airline at Manchester–Boston Regional Airport. This major low-cost American airline connects Manchester with popular resort destinations in Florida. Southwest Airlines takes customers to Fort Lauderdale-Hollywood International Airport, Orlando International Airport, and Tampa International Airport. By offering direct trips to Baltimore/Washington International Thurgood Marshall Airport, Southwest Airlines creates a direct route into the Baltimore and Washington D.C. area. This busy low-cost carrier can also be used to get to Chicago's secondary airport, Midway. Anyone in New Hampshire who wants to visit the biggest casino city in the world can also use Southwest Airlines for seasonal flights to McCarran International Airport in Las Vegas. With additional service to Denver, Southwest Airlines is the only company in Manchester, NH to offer trips to the West Coast.
United Airlines links Manchester–Boston Regional Airport with some of the largest metropolitan areas in the United States. By operating direct trips to Newark Liberty International Airport, United Airlines takes Manchester's passengers into the Northern New Jersey part of the NY Metropolitan Area. This major domestic airline also operates non-stop flights to the main airports in Chicago, Cleveland, and Washington District of Columbia.
US Airways invites passengers at Manchester–Boston Regional Airport into some of the largest cities on the East Coast. US Airways Express service includes flights to Charlotte/Douglas International Airport and Philadelphia International Airport. Additionally, the nation's capital district can also be reached all year long via US Airways service at New Hampshire's busiest airport.